“Dr Argyriou is so compassionate and empathetic. She listens to concerns and has a plan.”
DONNA S.
Pain Management Doctor on Long Island
Achieve Lasting Neck and Back Pain Relief With Dr. Argyriou
Dr. Antigone Argyriou, MD, FAAPMR, is a double-board-certified pain management specialist. She offers cutting-edge, minimally invasive solutions for acute and chronic pain to help patients restore function, improve quality of life and get lasting relief.
Professional affiliations
About Dr. Antigone Argyriou, MD, FAAPMR
Long Island Pain Management Specialist
Pain management physician Dr. Antigone Argyriou takes a patient-first, multimodal approach to treating pain. Simply put, she addresses the many different factors that contribute to pain and dysfunction, rather than focusing on just one.
With advanced training in physical medicine, rehabilitation, and interventional pain medicine, Dr. Argyriou develops personalized care plans that combine the safest, most effective therapies for each patient’s unique needs. This might include targeted injections, rehabilitation strategies, lifestyle recommendations, and other minimally invasive treatments designed to restore function and improve quality of life.
Her expertise includes epidural steroid injections, nerve blocks, joint injections, radiofrequency ablation, spinal cord stimulation, platelet-rich plasma injections and more. Whether addressing neck pain, back pain, joint pain, or nerve-related discomfort, Dr. Argyriou’s goal is to help patients return to active living without major surgery.
Undergraduate Degree
Hofstra University, Bachelors of English Literature and Biology
Hempstead, NY
Medical Degree
Saba University School of Medicine
Saba, Dutch Caribbean
Residency
Physical Medicine and Rehabilitation residency at Montefiore Medical
Center
Bronx, NY
Fellowship
Pain Medicine fellowship at Montefiore Medical Center
Bronx, NY
Pain Management Specialist
Dr. Argyriou’s Education & Training
Dr. Antigone Argyriou attended medical school at Saba University and completed her internship in Internal Medicine at Nassau University Medical Center, where she was honored with the Intern of the Year Award.
She then went on to complete her residency in Physical Medicine and Rehabilitation at Montefiore Medical Center for the Albert Einstein College of Medicine, serving as chief resident in her final year. Following residency, Dr. Argryriou pursued a fellowship in Pain Medicine and later obtained certification in medical acupuncture.
Leadership & Service
Dr. Argyriou has consistently demonstrated leadership and dedication beyond her practice. She is very active in advocacy work and is a past president of the New York State Society of Physical Medicine & Rehabilitation.
She was appointed to the American Academy of Physical Medicine & Rehabilitation (AAPM&R) Reimbursement Policy and Regulatory Affairs Committee and currently serves as the alternate CPT advisor for Physical Medicine & Rehabilitation for the American Medical Association. More recently, she was appointed to the International Pain and Spine Intervention Society’s Advocacy and Coding and Reimbursement Committee.
At a local level, she serves on the Board of the Suffolk County Medical Society, where she plays an active role in public education, community service, and health advocacy. She serves as a delegate to the Medical Society of the State of New York (MSSNY) and its House of Delegates. In this role, she represents the voices of local doctors, reviews proposals for changes in healthcare policy, and helps shape the official positions of the state medical society by debating ideas and voting on measures that can directly impact how medicine is practiced and how patients receive care across New York State.
Professional Experience
Before joining Spine Medicine & Surgery of Long Island, Dr. Argyriou worked at a large neurology practice where she spearheaded the pain medicine program and served as Director of Pain Management. She has since continued to expand access to advanced, non-surgical pain solutions to help patients overcome debilitating conditions and regain their independence.
Personal Interests
In her spare time, it’s important to Dr. Argyriou that she practices what she preaches by staying healthy and active. She’s interested in the anti-inflammatory diet and likes to explore new, delicious, but healthy recipes.
She also indulges her athletic side by going to the gym, swimming, walking her dog, riding her bike and, most recently, coaching a girls’ youth basketball team. When relaxing, you can find her reading fiction novels and doing puzzles.
Dr. Argyriou’s Commitment to You
Dr. Argyriou’s mission is simple: to provide compassionate, evidence-based, effective pain management. By addressing the physical, functional, and lifestyle aspects of pain, she helps patients not just find relief but return to doing what they love most.
Awards
2025 Castle Connolly Top Doctor
Town of Oyster Bay Women of Distinction Award (2025)
Boston Scientific: Basivertebral Nerve Ablation Center of Excellence Designation (2024)
New York Super Doctor: Rising Star (Super Doctors® 2024)
North America’s Greek American 40 Under 40 Award, Greek America Foundation (2022)
Excellence in Leadership & Service Award, New York Society of Physical Medicine & Rehabilitation (2019)
Excellence in Leadership & Service Award, New York Society of Physical Medicine & Rehabilitation (2017)
Leo M. Davidoff Society Award for significant contribution to medical education (2015)
Dr. Argyriou’s Specialties
Solutions for Joint and Spine Pain Management
Trigger Point Injections
Trigger points are hard knots of muscle that contract but aren’t able to relax, which can cause chronic pain and decreased mobility. Trigger points may develop due to injury, overuse, stress and anxiety. Dr. Argyriou offers trigger point injections to help relax the muscles and provide relief.
Radiofrequency Ablations
Radiofrequency ablation is a long-term solution that works by ablating, or interrupting, the pain signals from the nerves that are causing your neck or back pain. After locating the target nerve with a facet joint injection or a medial branch block, Dr. Argyriou may recommend this minimally invasive procedure.
Epidural Steroid Injections
As a Long Island pain management doctor, Dr. Argyriou is an expert in epidural steroid injections. The injections are a common non-surgical treatment for irritated spinal nerves. She injects a powerful anti-inflammatory medication into the space around the spinal cord to reduce inflammation, pain and numbness.
Intracept® for Lower Back Pain
Dr. Argyriou is one of the first providers to offer the revolutionary Intracept procedure, a minimally invasive, implant-free treatment for chronic lower back pain. By ablating the basivertebral nerve (BVN), this procedure provides long-term relief for vertebrogenic pain—an issue that previously had very few treatment options. She has been designated a Center of Excellence for Intracept by Boston Scientific and has performed more cases than most physicians worldwide, reflecting her expertise and leadership in advancing this innovative therapy.
In the Media
Spotlight on Dr. Argyriou
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Behind the Scenes (Reels)
Client case study
Epidural Steroid Injections, Facet injections, MISS & Intracept®
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Looking for Lasting Back Pain Relief on Long Island?
Don’t let pain control your life. Schedule a consultation with Dr. Antigone Argyriou today to explore your non-surgical treatment options.







